Saturday, April 19, 2014

Mixing of genes or reassortatsioon should be mainly based on modern knowledge of piglets in the bod

Becomes like a woman's pleasure: influenza | Horizon
Yesterday, April 30, the World Health Organization recently declared the disease and the causative influenza pandemic fear-provoking influentsaviirus officially wine fridge named A (H1N1). As of April 30 was officially Virus / Laboratory findings in 11 countries and 257 cases, of which 109 cases in the United States and 97 in Mexico (death by 1 and 7). In addition to Mexico and the United States have influenza A (N1H1) cases reported in Austria (1 laboratory-identified leader), Canada (19), Germany (3), Israel (2), Netherlands (1), New Zealand (3), Spain ( 13), Switzerland (1) and the United Kingdom (8). The situation järlib and maps among other things, Google Maps.
Swine flu dashing entry in the shadow of the H5N1 bird flu would be like a forgotten, for example, but not until April 23, the Egyptian health authorities reported four-year-old boy's illness precisely the bird flu. Egypt bird flu detected in 67 juhtmist 23 have been fatal. 2009th year, the World Health Organisation, the worldwide H5N1 flu found in 26, 7 of them are fatal
Influenza viruses, and if such tales in the past year sajakonnal wrote some time ago, then basically the fear of SARS in the shadow of the faculty of the University of Tartu, Medical Doctor Tõnis Karki article "A piece of bad news, which is packed with protein." wine fridge By the way - the First World War was caused by the pandemic influenza virus type H1N1. Influenza-being of the 20th century, wrote at the time Tõnis Karki following:
Influenza virus (the virion) genome is a single stranded RNA molecule. Its genome is a characteristic of the fact that there is not a single integrated linear RNA chain, wine fridge the influenza virus RNA genome is segmented into eight separate paragraph. So - a comprehensive influenza virus protein shell, or capsid inside the lies of the eight RNA segments (shown in the figure is the different lengths of these lines). Tubular structures are formed on the surface of influenza virus unique, whereby the virion attaches to the cell surface. In one structure called wine fridge the neuraminidase (NA), but another named hemagglutinin (HA). HA and NA genes responsible for the synthesis of which are located in different segments of the genome (Figure shown in red and blue). wine fridge
Influenza is a characteristic of constant change. These changes take place primarily at the HA and NA molecules on primary change is due to mutations in the RNA. Such changes wine fridge are called antigenic drift. Just this antigenic drift is the reason why each subsequent year, the influenza virus is a little different than last year, and every year, why do we need a new flu vaccine.
Moreover, wine fridge antigenic drift of the offset is also antigenic. This phenomenon is much more serious than the drift - the change is extensive, basically due to the new NA or HA molecules on the surface of the emergence of influenza viruses. Indeed, now known as the five other HA subtypes, wine fridge only subtypes of how people have found HA1, HA2, and HA3. The remainder are present in birds and animals. Nine NA subtypes are isolated from the human NA1 and NA2. According to the HA and NA subtypes of influenza virus called from a specific formula: H1N1, H3N2. If a formula influenza virus circulating globally for a long time and is subject to antigenic drift, the human population will acquire some immunity against the virus type. This is the reason why the flu does not reach very drastic wine fridge forms.
However, among people with circulating influenza virus strains sometimes occur in large-scale change - antigenic wine fridge shift. As a new type of a lack of immunity in humans, wine fridge can such a drastic shift in the start of flu pandemics - such as the Spanish flu in 1918. Was that caused 20 million deaths.
Antigenic shift is due to the phenomenon known as the genetic reassortatsiooniks. Namely, a person may be infected with influenza strains in a certain wine fridge number of animals and birds, particularly water fowl. In particular, the piglets are those animals wine fridge who can get the virus at the same time as people as well as among strains circulating among birds. Simultaneous infection, it may happen that the defective viruses are packed in a certain "false", into the genome of birds from the HA or NA of the segment. wine fridge The result is a completely new influenza virus antigenic formula. For example, in Hong Kong in 1997 was a "new" strain of the H5N1 flu virus. wine fridge Such strains were apparently based on the "Russian" H1N1 Flu Formula, which took the place of the normal H1 molecular genetic reassortatsiooni result of H5 avian origin. Source of infection for humans were poultry.
Mixing of genes or reassortatsioon should be mainly based on modern knowledge of piglets in the body. However, it is often a reservoir of influenza virus the birds, especially ducks, which may maintain a certain strain of decades. The figure below shows how the modern According wine fridge to some views, the reservoir of influenza viruses are waterfowl survived 59 and 68 years.
NGO Nature Magazine

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